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Literature summary for 3.4.21.42 extracted from

  • Craig, T.J.; Levy, R.J.; Wasserman, R.L.; Bewtra, A.K.; Hurewitz, D.; Obtulowicz, K.; Reshef, A.; Ritchie, B.; Moldovan, D.; Shirov, T.; Grivcheva-Panovska, V.; Kiessling, P.C.; Keinecke, H.O.; Bernstein, J.A.
    Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks (2009), J. Allergy Clin. Immunol., 124, 801-808.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
C1 esterase inhibitor C1 esterase inhibitor inhibits components of the complement (specifically C1r and C1s), C1 esterase inhibitor concentrate given intravenously at a dose of 20 units/kg is an effective and safe treatment for acute abdominal and facial attacks in patients with hereditary angioedema Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
C1 esterase
-
 Homo sapiens
C1s
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction hereditary angioedema is caused by C1 esterase inhibitor deficiency Homo sapiens