Literature summary for 3.4.21.4 extracted from

Chaudhary, N.S.; Shee, C.; Islam, A.; Ahmad, F.; Yernool, D.; Kumar, P.; Sharma, A.K.
Purification and characterization of a trypsin inhibitor from Putranjiva roxburghii seeds (2008), Phytochemistry, 69, 2120-2126.

Search for more literature for 3.4.21.4

Inhibitors

Inhibitors	Comment	Organism	Structure
Putranjiva roxburghii trypsin inhibitor	highly potent inhibitor of bovine trypsin, trypsin inhibitory activity of Putranjiva roxburghii trypsin inhibitor is completely retained up to 70°C, above 70°C, there is a slight decrease in the inhibitory activity retaining almost 85% inhibitory activity up to 80°C, the inhibitory activity of Putranjiva roxburghii trypsin inhibitor falls sharply above 80°C with a loss of almost 80% inhibitory activity at 90°C, only a slight decrease of 5% in inhibitory activity is observed when Putranjiva roxburghii trypsin inhibitor is incubated for 2 h at 100 mM dithiothreitol	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-alpha-benzoyl-L-Arg-4-nitroanilide + H2O	-	Bos taurus	N-alpha-benzoyl-L-Arg + 4-nitroaniline	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000000014	-	Putranjiva roxburghii trypsin inhibitor	in 50 mM Tris-HCl buffer, pH 8.0 containing 20 mM CaCl2 and 0.001 N HCl, at 30°C	Bos taurus

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Release 2023.1 (January 2023)