Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-[4-(5-fluoro-3-methylbenzo[b]thiophen-2-yl)sulfonamido-3-methanesulfonylphenyl]thiazole-4-carboxylic acid | TY-51469, specific chymase inhibitor | Mesocricetus auratus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mesocricetus auratus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mesocricetus auratus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | - |
Mesocricetus auratus | angiotensin II + ? | - |
? | |
pro-matrix metalloprotease 9 + H2O | - |
Mesocricetus auratus | matrix metalloprotease 9 + ? | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | chymase may play a crucial role in the development of nonalcoholic steatohepatitis in hamsters | Mesocricetus auratus |