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Literature summary for 3.4.21.39 extracted from

  • Reimer, J.M.; Enoksson, M.; Samollow, P.B.; Hellman, L.
    Extended substrate specificity of opossum chymase - Implications for the origin of mast cell chymases (2008), Mol. Immunol., 45, 2116-2125.
    View publication on PubMed
Search for more literature for 3.4.21.39

Cloned(Commentary)

Cloned (Comment) Organism
expressed in 293-EBNA cells Monodelphis domestica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25000
-
 estimated from amino acid sequence Monodelphis domestica
30000
-
 SDS-PAGE Monodelphis domestica

Organism

Organism UniProt Comment Textmining
Monodelphis domestica
-
 short-tailed opossum
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Monodelphis domestica

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose bead chromatography and heparin-agarose column chromatography Monodelphis domestica

Source Tissue

Source Tissue Comment Organism Textmining
skin
-
 Monodelphis domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methoxy-succinyl-Ala-Ala-Pro-Met-p-nitroanilide + H2O low cleavage efficiency Monodelphis domestica methoxy-succinyl-Ala-Ala-Pro-Met + p-nitroaniline
-
 ?
methoxy-succinyl-Arg-Pro-Tyr-p-nitroanilide + H2O
-
 Monodelphis domestica methoxy-succinyl-Arg-Pro-Tyr + p-nitroaniline
-
 ?
additional information shows chymotryptic activity and a strong preference for Trp over Phe and Tyr in the P1 position Monodelphis domestica ?
-
 ?
N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide + H2O
-
 Monodelphis domestica N-succinyl-Ala-Ala-Pro-Phe + p-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
alpha-chymase
-
 Monodelphis domestica