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Literature summary for 3.4.21.37 extracted from

  • Novovic, S.; Andersen, A.M.; Nord, M.; Astrand, M.; Ottosson, T.; Jorgensen, L.N.; Hansen, M.B.
    Activity of neutrophil elastase reflects the progression of acute pancreatitis (2013), Scand. J. Clin. Lab. Invest., 73, 485-493.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme activity is associated with predicted severity of acute pancreatitis and acute pancreatitis-associated respiratory failure Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
alpha1-antitrypsin
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
Homo sapiens ?
-
?
methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin + H2O
-
Homo sapiens methoxysuccinyl-Ala-Ala-Pro-Val + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
neutrophil elastase
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens enzyme activity is higher overall in patients with predicted severe acute pancreatitis than in those with predicted mild acute pancreatitis. Patients with respiratory failure have higher enzyme activity than those without up