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Literature summary for 3.4.21.37 extracted from

  • Schmelzer, C.E.; Jung, M.C.; Wohlrab, J.; Neubert, R.H.; Heinz, A.
    Does human leukocyte elastase degrade intact skin elastin? (2012), FEBS J., 279, 4191-4200.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Homo sapiens
-
?
-
?
tropoelastin + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
Homo sapiens ?
-
?
tropoelastin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
HLE
-
Homo sapiens

General Information

General Information Comment Organism
physiological function human leukocyte elastase is not a driving force for elastolysis, but may promote further breakdown of elastic fibers after the action of other enzymes such as cathepsin G Homo sapiens