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Literature summary for 3.4.21.37 extracted from
- Neutrophil elastase and syndecan shedding contribute to antithrombin depletion in murine anthrax (2008), FEMS Immunol. Med. Microbiol., 54, 309-318.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | blood plasma antithrombin levels are rapidly depleted in Bacillus anthracis Sterne spore-challenged mice, concomitant with elevation of neutrophil elastase | Mus musculus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
SDS-PAGE | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | Mus musculus | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| antithrombin + H2O | leukocyte elastase inactivates antithrombin by a specific and limited proteolytic cleavage | Mus musculus | ? | - |
? | |
| Elastin + H2O | - |
Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| neutrophil elastase | - |
Mus musculus |
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Release 2023.1 (January 2023)
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