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Literature summary for 3.4.21.37 extracted from

  • Balduyck, M.; Piva, F.; Mizon, C.; Maes, P.; Malki, N.; Gressier, B.; Michalski, C.; Mizon, J.
    Human leucocyte elastase (HLE) preferentially cleaves the heavy chain H2 of inter-alpha-trypsin inhibitor (ITI) (1993), Biol. Chem. Hoppe-Seyler, 374, 895-901.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2 heavy chain of inter-alpha-trypsin inhibitor + H2O
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Homo sapiens additional information early cleavage products consists of heavy chain H1 linked to the light chain, known as bikunin ?