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Literature summary for 3.4.21.35 extracted from

  • Oliva, M.L.V.; Andrade, S.; Batista, I.F.C.; Sampaio, M.U.; Juliano, M.; Fritz, H.; Auerswald, E.A.; Sampaio, C.A.M.
    Human plasma kallikrein and tissue kallikrein binding to a substrate based on the reactive site of a factor Xa inhibitor isolates from Bauhinia ungulata seeds (1999), Immunopharmacology, 45, 145-149.
    View publication on PubMed
Search for more literature for 3.4.21.35

Inhibitors

Inhibitors Comment Organism Structure
additional information no inhibition by Bauhinia ungulata factor Xa inhibitor, and Bauhinia variegata trypsin inhibitor Sus scrofa
Soybean trypsin inhibitor no inhibition Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Sus scrofa
0.00023
-
 o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa
0.0005
-
 o-aminobenzoyl-VMIAALPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa
0.0007
-
 o-aminobenzoyl-LPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa
0.0027
-
 o-aminobenzoyl-LPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Sus scrofa
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
o-aminobenzoyl-LPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O shortened, quenched fluorescent substrate, synthesized based on Bauhinia ungulata factor Xa inhibitor reactive sequence site Sus scrofa ?
-
 ?
o-aminobenzoyl-LPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O shortened, quenched fluorescent substrate, synthesized based on Bauhinia ungulata factor Xa inhibitor reactive sequence site Sus scrofa ?
-
 ?
o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O low activity Sus scrofa ?
-
 ?
o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O quenched fluorescent substrate, synthesized based on Bauhinia ungulata factor Xa inhibitor reactive sequence site Sus scrofa ?
-
 ?
o-aminobenzoyl-VMIAALPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O low activity Sus scrofa ?
-
 ?
o-aminobenzoyl-VMIAALPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O quenched fluorescent substrate, synthesized based on Bauhinia ungulata factor Xa inhibitor reactive sequence site Sus scrofa ?
-
 ?
polypeptide + H2O
-
 Sus scrofa peptides
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Sus scrofa
0.0005
-
 o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa
0.004
-
 o-aminobenzoyl-VMIAALPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa
0.014
-
 o-aminobenzoyl-LPRTMQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa
0.032
-
 o-aminobenzoyl-LPRTMFIQ-N-(2,4-dinitrophenyl)ethylene diamine pH 8.0, 37°C Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Sus scrofa