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Literature summary for 3.4.21.35 extracted from

  • Yao, Y.Y.; Yin, H.; Shen, B.; Smith, R.S.; Liu, Y.; Gao, L.; Chao, L.; Chao, J.
    Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3beta pathway (2008), Cardiovasc. Res., 80, 354-364.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Rattus norvegicus heart Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens tissue kallikrein stimulates capillary tube formation and promotes cell migration of cultured endothelial cells, expression of human tissue kallikrein in rat heart reduces infarct size after myocardial infarction, tissue kallikrein inhibits GSK-3beta activity and stimulates vascular endothelial growth factor and vascular endothelial growth factor receptor-2 expression in cultured endothelial cells ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
aortic endothelial cell
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 Homo sapiens
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HCAEC cell
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information tissue kallikrein stimulates capillary tube formation and promotes cell migration of cultured endothelial cells, expression of human tissue kallikrein in rat heart reduces infarct size after myocardial infarction, tissue kallikrein inhibits GSK-3beta activity and stimulates vascular endothelial growth factor and vascular endothelial growth factor receptor-2 expression in cultured endothelial cells Homo sapiens ?
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 ?