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Literature summary for 3.4.21.35 extracted from
- The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions (2001), Biol. Chem., 382, 5-14.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| genetic organization and structure of the kallikrein gene family, clustered on chromosome 19q13.3-q13.4 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| kininogen + H2O | Homo sapiens | - |
kallidin + kinin heavy chain + kinin light chain | - |
? |  |
| polypeptide + H2O | Homo sapiens | - |
peptides | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P06870 | gene KLK1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endometrium | - |
Homo sapiens | - |
| kidney | - |
Homo sapiens | - |
| ovary | - |
Homo sapiens | - |
| pancreas | - |
Homo sapiens | - |
| salivary gland | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| kininogen + H2O | - |
Homo sapiens | kallidin + kinin heavy chain + kinin light chain | - |
? | |
| low-molecular-weight kininogen + H2O | - |
Homo sapiens | kallidin + kinin | kallidin is Lys-bradykinin | ? | |
| polypeptide + H2O | - |
Homo sapiens | peptides | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| K1 | - |
Homo sapiens |
| tissue kallikrein | - |
Homo sapiens |
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