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Literature summary for 3.4.21.34 extracted from

  • Hayashi, J.; Salomon, D.R.; Hugli, T.E.
    Elevated kallikrein activity in plasma from stable liver transplant recipients (2002), Int. Immunopharmacol., 2, 1667-1680.
    View publication on PubMed
Search for more literature for 3.4.21.34

Activating Compound

Activating Compound Comment Organism Structure
Lima bean trypsin inhibitor
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Aprotinin
-
 Homo sapiens
benzamidine
-
 Homo sapiens
D-Phe-Phe-Arg-chloromethylketone complete inhibition at 0.01 mM Homo sapiens
futhan
-
 Homo sapiens
human C1 esterase inhibitor 63% inhibition at 0.04 mg/ml Homo sapiens
additional information no inhibition by hirudin, bdellin, and corn trypsin inhibitor Homo sapiens
Soybean trypsin inhibitor
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble plasma, in orthotopic liver transplant recipients in complex with alpha-2-macroglonulin Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme activity is enhanced in orthotopic liver transplant recipients ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma from normal persons and orthotopic liver transplant recipients Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-AGLTR-4-nitroanilide + H2O chromogenic substrate based on the C1s cleavage site in complement component C4 Homo sapiens Ac-AGLTR + 4-nitroaniline
-
 ?
complement component C4 + H2O substrate is only cleaved in vitro, not in vivo Homo sapiens ?
-
 ?
D-Pro-Phe-Arg-4-nitroanilide + H2O
-
 Homo sapiens D-Pro-Phe-Arg + 4-nitroaniline
-
 ir
additional information enzyme activity is enhanced in orthotopic liver transplant recipients Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 86000-88000, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4 7.8 assay at Homo sapiens