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Literature summary for 3.4.21.27 extracted from

  • Cheng, Q.; Tucker, E.; Pine, M.; Sisler, I.; Matafonov, A.; Sun, M.; White-Adams, T.; Smith, S.; Hanson, S.; McCarty, O.; Renne, T.; Gruber, A.; Gailani, D.
    A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo (2010), Blood, 116, 3981-3989.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.27

Activating Compound

Activating Compound Comment Organism Structure
factor XIIa
-
 Mus musculus
additional information antibody 14E11 exerts an inhibitory effect on fXI activation, but not fXIa activity Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor IX + H2O Mus musculus
-
 activated factor IX + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor IX + H2O
-
 Mus musculus activated factor IX + ?
-
 ?
Gly-Gly-L-Arg-7-amido-4-methylcoumarin + H2O
-
 Mus musculus Gly-Gly-L-Arg + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
factor XIa
-
 Mus musculus
FXIa
-
 Mus musculus