Literature summary for 3.4.21.27 extracted from

Livnat, T.; Tamarin, I.; Mor, Y.; Winckler, H.; Horowitz, Z.; Korianski, Y.; Bar-Zakay, B.; Seligsohn, U.; Salomon, O.
Recombinant activated factor VII and tranexamic acid are haemostatically effective during major surgery in factor XI-deficient patients with inhibitor antibodies (2009), Thromb. Haemost., 102, 487-492.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood plasma	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
factor XI	-	Homo sapiens
FXI	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	patients who have a very severe FXI deficiency are prone to development of inhibitor antibodies. During major surgeries, a single low dose of recombinant activated factor VII and tranexamic acid secure normal haemostasis in patients with severe FXI deficiency who can not receive blood products	Homo sapiens

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Release 2023.1 (January 2023)