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Literature summary for 3.4.21.26 extracted from

  • Walter, R.
    Partial purification and characterization of post-proline cleaving enzyme: enzymatic inactivation of neurohypophyseal hormones by kidney preparations of various species (1976), Biochim. Biophys. Acta, 422, 138-158.
    View publication on PubMed
Search for more literature for 3.4.21.26

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Ovis aries
4-Chloromercuriphenylsulfonate
-
 Ovis aries
Ca2+
-
 Ovis aries
Co2+
-
 Ovis aries
L-1-tosylamido-2-phenylethylchloromethyl ketone
-
 Ovis aries
additional information
-
 Ovis aries
Zn2+
-
 Ovis aries

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
67000
-
 2 * 67000, SDS-PAGE Ovis aries
115000
-
 gel filtration Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Ovis aries

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Ovis aries
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.4
-
-
 Ovis aries

Storage Stability

Storage Stability Organism
-20°C or -70°C, 1 mM EDTA, dithiothreitol, pH 7.0, several months Ovis aries

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cleavage of Pro-X bond Ovis aries ?
-
 ?
oxytocin + H2O
-
 Ovis aries CYIQNCP + L-Leu-Gly
-
 ?
vasopressin + H2O
-
 Ovis aries inactivated vasopressin + dipeptide
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 67000, SDS-PAGE Ovis aries

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8
-
 Ovis aries