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Literature summary for 3.4.21.26 extracted from

  • OReilly, P.J.; Hardison, M.T.; Jackson, P.L.; Xu, X.; Snelgrove, R.J.; Gaggar, A.; Galin, F.S.; Blalock, J.E.
    Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen (2009), J. Neuroimmunol., 217, 51-54.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
LPS
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
Homo sapiens
-
peripheral blood cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen + H2O after enzyme activation with LPS Homo sapiens N-acetyl-Pro-Gly-Pro + ?
-
?
collagen + H2O after enzyme activation with LPS Homo sapiens Pro-Gly-Pro + ?
-
?
Z-Gly-Pro-4-nitroanilide + H2O assay at 37°C Homo sapiens Z-Gly-Pro + p-nitroaniline
-
?

Subunits

Subunits Comment Organism
monomer
-
Homo sapiens

Synonyms

Synonyms Comment Organism
prolyl endopeptidase
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens