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Literature summary for 3.4.21.26 extracted from

  • Myoehaenen, T.T.; Venaelaeinen, J.I.; Tupala, E.; Garcia-Horsman, J.A.; Miettinen, R.; Maennistoe, P.T.
    Distribution of immunoreactive prolyl oligopeptidase in human and rat brain (2007), Neurochem. Res., 32, 1365-1374.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme plays a role in inositol 1,4,5-triphosphate signaling and in the actions of antidepressants, POP inhibitors have antiamnesic and neuroprotective properties, overview ?
-
?
additional information Rattus norvegicus the enzyme plays a role in inositol 1,4,5-triphosphate signaling and in the actions of antidepressants, POP inhibitors have antiamnesic and neuroprotective properties, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
female and male Caucasian individuals
-
Rattus norvegicus
-
young, male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
brain distribution in brain tissues, immunohistochemic analysis, overview Homo sapiens
-
brain distribution in brain tissues, immunohistochemic analysis, overview Rattus norvegicus
-
brain cortex
-
Homo sapiens
-
caudate nucleus
-
Homo sapiens
-
caudate putamen
-
Homo sapiens
-
caudate putamen
-
Rattus norvegicus
-
cerebellum
-
Rattus norvegicus
-
hippocampus
-
Homo sapiens
-
hippocampus
-
Rattus norvegicus
-
additional information the distribution of the enzsm in brain tissue correlates with the distribution of the IP3-receptor Homo sapiens
-
additional information the distribution of the enzsm in brain tissue correlates with the distribution of the IP3-receptor Rattus norvegicus
-
substantia nigra
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme plays a role in inositol 1,4,5-triphosphate signaling and in the actions of antidepressants, POP inhibitors have antiamnesic and neuroprotective properties, overview Homo sapiens ?
-
?
additional information the enzyme plays a role in inositol 1,4,5-triphosphate signaling and in the actions of antidepressants, POP inhibitors have antiamnesic and neuroprotective properties, overview Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
More the enzyme belongs to the POP family of serine proteases, family S9 of clan SC Homo sapiens
More the enzyme belongs to the POP family of serine proteases, family S9 of clan SC Rattus norvegicus
POP
-
Homo sapiens
POP
-
Rattus norvegicus
prolyl endopeptidase
-
Homo sapiens
prolyl endopeptidase
-
Rattus norvegicus