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Literature summary for 3.4.21.22 extracted from

  • Yang, L.; Rezaie, A.R.
    Residues of the 39-loop restrict the plasma inhibitor specificity of factor IXa (2013), J. Biol. Chem., 288, 12692-12698.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information factor IXa is resistant to inhibition by the plasma inhibitors protein Z-dependent protease inhibitor and tissue factor pathway inhibitor Bos taurus
additional information factor IXa is resistant to inhibition by the plasma inhibitors protein Z-dependent protease inhibitor and tissue factor pathway inhibitor Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Factor X + H2O Mus musculus
-
Factor Xa + ?
-
?
Factor X + H2O Bos taurus
-
Factor Xa + ?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Mus musculus
-
blood plasma
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Factor X + H2O
-
Mus musculus Factor Xa + ?
-
?
Factor X + H2O
-
Bos taurus Factor Xa + ?
-
?
L-Leu-Gly-L-Arg-4-nitroanilide + H2O FIXa-specific chromogenic substrate CBS 31.39 Mus musculus L-Leu-Gly-L-Arg + 4-nitroaniline
-
?
L-Leu-Gly-L-Arg-4-nitroanilide + H2O FIXa-specific chromogenic substrate CBS 31.39 Bos taurus L-Leu-Gly-L-Arg + 4-nitroaniline
-
?

Synonyms

Synonyms Comment Organism
factor IXa
-
Mus musculus
factor IXa
-
Bos taurus
FIXa
-
Mus musculus
FIXa
-
Bos taurus