Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Factor VIIIa | binding curves of FIXa and FVIIIa, binding of factor VIIIa with engineered disulfide bond resulting in a more stable FVIIIa: C662C1828 FVIIIa binds with similar affinity to that of wild-type FVIIIa, while C664-C1826 FVIIIa binds to FIXa with a significantly lower affinity, binding structures, overview | Homo sapiens | |
Phospholipids | the vesicles binding the enzyme consist of 40% phosphatidylcholine, 20% phosphatidylserine, and 40% phosphatidylethanolamine | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor X + H2O | Homo sapiens | - |
activated factor X + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | from plasma | Homo sapiens | - |
plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor X + H2O | - |
Homo sapiens | activated factor X + ? | - |
? | |
factor X + H2O | proteolytic activity, factor IXa acts as part of the FXase complex with factor VIIIa on the surface of phospholipid vesicles, overview | Homo sapiens | activated factor X + ? | - |
? |