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Literature summary for 3.4.21.22 extracted from
- Formation of factors IXa and Xa by the extrinsic pathway: differential regulation by tissue factor pathway inhibitor and antithrombin III (2004), J. Biol. Chem., 279, 17241-17249.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| factor VIIa/tissue factor | - |
Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0045 | - |
Factor X | in the presence of recombinant tissue factor protein and vesicles composed of 75% (w/w) L-alpha-phosphatidylcholine and 25% (w/w) L-alpha-phosphatidylserine | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| factor X + H2O | - |
Homo sapiens | factor Xa | - |
? |  |
| methoxycarbonyl-D-cyclohexylglycyl-glycyl-L-arginyl-p-nitroanilide + H2O | - |
Homo sapiens | methoxycarbonyl-D-cyclohexylglycyl-glycyl-L-arginine + p-nitroaniline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| factor IXabeta | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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