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Literature summary for 3.4.21.22 extracted from

  • Fujikawa, K.; Legaz, M.E.; Kato, H.; Davie, E.W.
    The mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa (activated plasma thromboplastin antecedent) (1974), Biochemistry, 13, 4508-4516.
    View publication on PubMed
Search for more literature for 3.4.21.22

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
16600
-
 1 * 27300 + 1 * 16600, SDS-PAGE Bos taurus
27300
-
 1 * 27300 + 1 * 16600, SDS-PAGE Bos taurus
46500
-
 SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor X + H2O Bos taurus a chymotrypsin homologue, and one of the gamma-carboxyglutamic acid-containing blood coagulation factors. The proenzyme factor IX is activated by factor XIa ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Reaction

Reaction Comment Organism Reaction ID
Selective cleavage of Arg-/-Ile bond in factor X to form factor Xa free of thrombin activity Bos taurus
a

Source Tissue

Source Tissue Comment Organism Textmining

Storage Stability

Storage Stability Organism
-20°C, 0.05 M imidazole buffer, pH 6.0, 0.2 M NaCl, no loss of activity after several months Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor X + H2O a chymotrypsin homologue, and one of the gamma-carboxyglutamic acid-containing blood coagulation factors. The proenzyme factor IX is activated by factor XIa Bos taurus ?
-
 ?
factor X + H2O
-
 Bos taurus factor Xa
-
 ?

Subunits

Subunits Comment Organism
dimer 1 * 27300 + 1 * 16600, SDS-PAGE Bos taurus

Synonyms

Synonyms Comment Organism
activated factor IX
-
 Bos taurus