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Literature summary for 3.4.21.21 extracted from

  • Taketomi, T.; Szlam, F.; Bader, S.O.; Sheppard, C.A.; Levy, J.H.; Tanaka, K.A.
    Effects of recombinant activated factor VII on thrombin-mediated feedback activation of coagulation (2008), Blood Coagul. Fibrinolysis, 19, 135-141.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
thrombinogen + H2O Homo sapiens antifibrinolytic effect of the enzyme in relation to the activity of thrombin, regulation, overview thrombin + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification factor VII is activated by thrombin Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
thrombinogen + H2O
-
Homo sapiens thrombin + ?
-
?
thrombinogen + H2O antifibrinolytic effect of the enzyme in relation to the activity of thrombin, regulation, overview Homo sapiens thrombin + ?
-
?

Synonyms

Synonyms Comment Organism
activated factor VII
-
Homo sapiens
FIIa
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens