Application | Comment | Organism |
---|---|---|
medicine | cathepsin G as potential therapeutic target | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-tosyl-L-phenylalanine chloromethyl ketone | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
tumor cells implanted on the dorsal skin flap over the calvaria of female mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast adenocarcinoma cell line | C166 tumor cells | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
cathepsin G | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | up-regulated at the tumor-bone interface | up |
General Information | Comment | Organism |
---|---|---|
malfunction | inhibition of cathepsin G reduces active TGF-beta at the tumor-bone interface | Mus musculus |
physiological function | cathepsin G is activating pro-MMP9, involved in enhanced TGF-betra signaling | Mus musculus |