Cloned (Comment) | Organism |
---|---|
expressed in HEK293-T cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
A73T | diminished activity | Homo sapiens |
G217S | specific activity is about 7% of the wild type enzyme | Homo sapiens |
additional information | deletion mutant K247_R254del shows diminished activity | Homo sapiens |
Q48R | mutant shows about 30% activity of the wild type enzyme | Homo sapiens |
R254W | shows about 50% of wild-type activity | Homo sapiens |
R37Q | mutant shows essentially normal activity and secretion (about 82-88% activity of the wild type enzyme) | Homo sapiens |
V235I | CTRC activity secreted by cells transfected with variant V235I is moderately reduced (about 65% of the wild type enzyme) | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreas | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
CTRC | - |
Homo sapiens |