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Literature summary for 3.4.21.119 extracted from

  • Planque, C.; Li, L.; Zheng, Y.; Soosaipillai, A.; Reckamp, K.; Chia, D.; Diamandis, E.P.; Goodglick, L.
    A multiparametric serum kallikrein panel for diagnosis of non-small cell lung carcinoma (2008), Clin. Cancer Res., 14, 1355-1362.
    View publication on PubMed

Application

Application Comment Organism
medicine a multiparametric panel of kallikrein markers for lung cancer diagnosis with relatively good accuracy is provided Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
serum the clinical value of 11 members of the tissue kallikrein family as potential biomarkers for lung cancer diagnosis are analyzed: Serum specimens from 51 patients with non-small cell lung cancer and from50 healthy volunteers are collected. Samples are analyzed for 11 kallikreins (KLK1, KLK4-8, and KLK10-14) by specific ELISA. compared with sera from normal subjects, sera of patients with non-small cell lung cancer have lower levels of KLK5, KLK7, KLK8, KLK10, and KLK12, and higher levels of KLK11, KLK13, and KLK14. KLK11, KLK12, KLK13, and KLK14 are associated with higher risk of non-small cell lung cancer as determined by univariate analysis and confirmed by multivariate analysis Homo sapiens
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Synonyms

Synonyms Comment Organism
KLK13
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Homo sapiens