Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.117 extracted from

  • Walker, F.; Nicole, P.; Jallane, A.; Soosaipillai, A.; Mosbach, V.; Oikonomopoulou, K.; Diamandis, E.P.; Magdolen, V.; Darmoul, D.
    Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer (2014), Biol. Chem., 395, 1075-1086.
    View publication on PubMed
Search for more literature for 3.4.21.117

Cloned(Commentary)

Cloned (Comment) Organism
enzyme overexpression in HT-29 cells resulting in increased cell proliferation Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular the enzyme is secreted Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic adenocarcinoma cell
-
 Homo sapiens
-
colonic cancer cell colon cancer cell lines and colonic tumors Homo sapiens
-
additional information no expression in healthy colon epithelium Homo sapiens
-

Synonyms

Synonyms Comment Organism
kallikrein-related peptidase 7
-
 Homo sapiens
KLK7
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function serine proteases of the tissue kallikrein-related peptidases family are implicated in tumorigenesis, kallikrein-related peptidase 7 is a proliferative factor that is aberrantly expressed in human colon cancer and involved in cell proliferation in vitro and in vivo Homo sapiens