Literature summary for 3.4.21.117 extracted from

Baretton, G.; Luther, T.; Tjan-Heijnen, V.C.; Talieri, M.; Schmitt, M.; Sweep, F.C.; Span, P.N.; Magdolen, V.
Quantitative reverse transcription-PCR assay for detection of mRNA encoding full-length human tissue kallikrein 7: prognostic relevance of KLK7 mRNA expression in breast cancer (2006), Clin. Chem., 52, 1070-1079.

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Application

Application	Comment	Organism
diagnostics	the enzyme might be a prognostic biomarker for breast cancer	Homo sapiens
medicine	expression of full-length KLK7 mRNA may represent a new prognostic marker in breast cancer disease	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
gene KLK7, overexpression in breast cancer cell lines aMCF-7, OVMZ-6, and MDA-231, quantitative expression analysis in wild-type native cells and in transfected cells, overview	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	high enzyme activity shows a significantly better prognosis in breast cancer	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P49862	-	-
Homo sapiens	P49862	gene KLK7	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast cancer cell	enzyme expression analysis in 155 patients, overview	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	high enzyme activity shows a significantly better prognosis in breast cancer	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
kallikrein 7	-	Homo sapiens
tissue kallikrein 7	-	Homo sapiens

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Release 2023.1 (January 2023)