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Literature summary for 3.4.21.117 extracted from

  • Planque, C.; de Monte, M.; Guyetant, S.; Rollin, J.; Desmazes, C.; Panel, V.; Lemarie, E.; Courty, Y.
    KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer (2005), Biochem. Biophys. Res. Commun., 329, 1260-1266.
    View publication on PubMed
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Application

Application Comment Organism
medicine kallikrein 7 may be useful in clinics as biomarkers for the detection and monitoring of non-small cell lung cancer Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens gene expression might be involved in lung tumorigenesis ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung highest concentrations of KLK7 mRNA are found in the non-cancerous tissue of patients with (well or moderately) differentiated tumors and the lowest in those with poorly differentiated tumors Homo sapiens
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lung adenocarcinoma cell expression of KLK7 is decreased Homo sapiens
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lung cancer cell KLK7 is strongly expressed in the tissue of patients with squamous cell carcinoma and differentiated tumors Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information gene expression might be involved in lung tumorigenesis Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
KLK7
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 Homo sapiens