Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Soybean trypsin inhibitor | strong inhibition | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
9000 | - |
x * 9000 + x * 19000, SDS-PAGE | Rattus norvegicus |
19000 | - |
x * 9000 + x * 19000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | Rattus norvegicus | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
cleavage of proteins with aromatic side chains in the P1 position | enzyme exhibits a marked preference for cleavage downstream of Arg residues | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
submandibular gland | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-Phe-Val-Arg-7-amido-4-methylcoumarin + H2O | - |
Rattus norvegicus | benzoyl-Phe-Val-Arg + 7-amino-4-methylcoumarin | - |
? | |
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Rattus norvegicus | benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
additional information | no kininogenase activity | Rattus norvegicus | ? | - |
? | |
additional information | enzyme exhibits a marked preference for cleavage downstream of Arg residues | Rattus norvegicus | ? | - |
? | |
o-aminobenzoyl-FRAPR-(2,4-dinitrophenyl)ethylenediamine + H2O | low activity | Rattus norvegicus | ? | - |
? | |
o-aminobenzoyl-FRLVR-(2,4-dinitrophenyl)ethylenediamine + H2O | low activity | Rattus norvegicus | o-aminobenzoyl-FR + LVR-(2,4-dinitrophenyl)ethylenediamine | - |
? | |
o-aminobenzoyl-SVIRRVQ-(2,4-dinitrophenyl)ethylenediamine + H2O | - |
Rattus norvegicus | ? | - |
? | |
o-aminobenzoyl-TSVIRRPQ-(2,4-dinitrophenyl)ethylenediamine + H2O | low activity | Rattus norvegicus | ? | - |
? | |
PFR-7-amido-4-methylcoumarin + H2O | best substrate | Rattus norvegicus | ? | - |
? | |
polypeptide + H2O | - |
Rattus norvegicus | peptides | - |
? | |
tert-butyloxycarbonyl-Leu-Gly-Arg-7-amido-4-methylcoumarin + H2O | - |
Rattus norvegicus | tert-butyloxycarbonyl-Leu-Gly-Arg + 7-amino-4-methylcoumarin | - |
? | |
tert-butyloxycarbonyl-Phe-Ser-Arg-7-amido-4-methylcoumarin + H2O | - |
Rattus norvegicus | tert-butyloxycarbonyl-Phe-Ser-Arg + 7-amino-4-methylcoumarin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 9000 + x * 19000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
tissue kallikrein | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | - |
assay at | Rattus norvegicus |