Karmarkar, M.G.; Santosh, K.; Vineetha, V.; Mehta, P.R.; Kaplan, E.; Yurecho, R.; Cleary, P.P.
Human immune response to streptococcal C5a peptidase in Indian children and adults (2006), Int. Congr. Ser., 1289, 54-57.
No PubMed abstract available
Application
Application |
Comment |
Organism |
medicine |
increased anti-SCPA IgG levels in rheumatic fever, rheumatic heart disease and acute glomerulo nephritis cases. The rise of anti-SCPA IgG observed in patients is irrespective of different emm types of group A streptococci strains isolated from these patients. Indian females show higher concentration of anti-SCPA antibodies than male patients. Anti-SCPA IgG1 and anti-SCPA IgG3 are the predominant subclasses of anti-SCPA antibody and clearly distinguish individuals with acute rheumatic fever from those free of streptococcal disease |
Streptococcus sp. |
Inhibitors
Inhibitors |
Comment |
Organism |
Structure |
additional information |
anti-SCPA antibodies can neutralize the activity of the enzyme in vitro and in vivo |
Streptococcus sp. |
|
Organism
Organism |
UniProt |
Comment |
Textmining |
Streptococcus sp. |
- |
group A streptococci |
- |
Synonyms
Synonyms |
Comment |
Organism |
SCPA |
- |
Streptococcus sp. |