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Literature summary for 3.4.21.110 extracted from

  • Purushothaman, S.S.; Park, H.; Cleary, P.P.
    Promotion of fibronectin independent invasion by C5a peptidase into epithelial cells in group A Streptococcus (2004), Indian J. Med. Res., 119, 44-47.
No PubMed abstract available
Search for more literature for 3.4.21.110

Application

Application Comment Organism
medicine acts as a potential invasin of group A streptococcus and promotes invasion independent of fibronectin Streptococcus sp.

Protein Variants

Protein Variants Comment Organism
additional information isogenic M1-mutant, expressses SCPA on cell surface Streptococcus sp.

Inhibitors

Inhibitors Comment Organism Structure
anti-ScpA antibody blocks internalization of streptococci and neutralizes the C5a peptidase acitvity, enabling recruitment of polymorphoneutrophil leukocytes to sites of infection Streptococcus sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
 Streptococcus sp. 9986
-

Organism

Organism UniProt Comment Textmining
Streptococcus sp.
-
 group A streptococcus strain 90 226 serotype M1
-

Synonyms

Synonyms Comment Organism
SCPA
-
 Streptococcus sp.