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Literature summary for 3.4.21.109 extracted from

  • Jin, J.S.; Cheng, T.F.; Tsai, W.C.; Sheu, L.F.; Chiang, H.; Yu, C.P.
    Expression of the serine protease, matriptase, in breast ductal carcinoma of Chinese women: correlation with clinicopathological parameters (2007), Histol. Histopathol., 22, 305-309.
    View publication on PubMed
Search for more literature for 3.4.21.109

Application

Application Comment Organism
diagnostics the enzyme might be a good biomarker in treatment of malignant breast tumors Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
 Homo sapiens 9986
-
cytosol
-
 Homo sapiens 5829
-
membrane transmembrane enzyme Homo sapiens 16020
-
additional information no enzyme in tumor surrounding stromal cells and the extracellular matrix, overview Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens matriptase cleaves and activates proteins implicated in the progression of cancer ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 Chinese women
-

Source Tissue

Source Tissue Comment Organism Textmining
breast fibroadenoma cell
-
 Homo sapiens
-
breast invasive ductal carcinoma cell of ductal carcinomas in situ, and grade I-III invasive ductal carcinomas Homo sapiens
-
epithelium surface epithelial cells Homo sapiens
-
additional information enzyme expression analysis in cancer cells, overview Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information matriptase cleaves and activates proteins implicated in the progression of cancer Homo sapiens ?
-
 ?