Application | Comment | Organism |
---|---|---|
medicine | HtrA2/Omi is associated with the pathogenesis of amyotrophic lateral sclerosis | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36000 | - |
Western blot, mature form | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
anterior horn | - |
Homo sapiens | - |
spinal cord | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
HtrA2/Omi | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | it is analyzed whether abnormal expression of HtrA2/Omi occurs in amyotrophic lateral sclerosis patients: abnormal accumulations of HtrA2/Omi may occur in several types of motor neuronal inclusions in the anterior horn from sporadic amyotrophic lateral sclerosis and Cu/Zn superoxide dismutase (SOD1)-related familial amyotrophic lateral sclerosis (FALS) cases, and that HtrA2/Omi may be associated with the pathogenesis of both types of amyotrophic lateral sclerosis | Homo sapiens |