Literature summary for 3.4.21.108 extracted from

Moisoi, N.; Klupsch, K.; Fedele, V.; East, P.; Sharma, S.; Renton, A.; Plun-Favreau, H.; Edwards, R.E.; Teismann, P.; Esposti, M.D.; Morrison, A.D.; Wood, N.W.; Downward, J.; Martins, L.M.
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response (2009), Cell Death Differ., 16, 449-464.

Search for more literature for 3.4.21.108

Application

Application	Comment	Organism
medicine	loss of HtrA2 function might contribute to the activation of a stress response of mitochondrial origin in the brain that promotes neurodegeneration	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrial membrane	-	Mus musculus	31966	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q8BHC7	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
MEF cell	-	Mus musculus	-
Neuro-2a cell	-	Mus musculus	-
neuron	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
HtrA2 serine protease	-	Mus musculus
Omi	-	Mus musculus

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Release 2023.1 (January 2023)