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Literature summary for 3.4.21.107 extracted from

  • Chitlaru, T.; Zaide, G.; Ehrlich, S.; Inbar, I.; Cohen, O.; Shafferman, A.
    HtrA is a major virulence determinant of Bacillus anthracis (2011), Mol. Microbiol., 81, 1542-1559.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
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-
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Bacillus anthracis Vollum
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Synonyms

Synonyms Comment Organism
high temperature requirement A protease
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Bacillus anthracis
HtrA
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Bacillus anthracis

General Information

General Information Comment Organism
malfunction disruption of the high temperature requirement A gene affects significantly the ability of the resulting mutants to withstand heat, oxidative, ethanol and osmotic stress, exhibit delayed proliferation, and show a decrease of over six orders of magnitude in virulence as compared with the parental wild type strain Bacillus anthracis
physiological function HtrA is a major virulence determinant of Bacillus anthracis Bacillus anthracis