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Literature summary for 3.4.21.107 extracted from

  • Sriraman, K.; Jayaraman, G.
    HtrA is essential for efficient secretion of recombinant proteins by Lactococcus lactis (2008), Appl. Environ. Microbiol., 74, 7442-7446.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
molecular biology instead of using an Lactococcus lactis htrA mutant, the reduction of the HtrA level in wild-type recombinant cultures of Lactococcus lactis by acid tolerace response (ATR) suppression may serve as a better strategy for the production of secreted recombinant proteins Lactococcus lactis

Protein Variants

Protein Variants Comment Organism
additional information htrA mutation in Lactococcus lactis (strain NZ9000htrA) leads to significant reduction of the efficiency of recombinant-protein secretion, as shown by recombinantly expressed streptokinase and nuclease in Lactococcus lactis Lactococcus lactis

Organism

Organism UniProt Comment Textmining
Lactococcus lactis
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Source Tissue

Source Tissue Comment Organism Textmining
additional information HtrA expression can be lowered by the suppression of the acid tolerance response (ATR) Lactococcus lactis
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Synonyms

Synonyms Comment Organism
HtrA
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Lactococcus lactis