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Literature summary for 3.4.21.107 extracted from

  • Lyon, W.R.; Caparon, M.G.
    Role for serine protease HtrA (DegP) of Streptococcus pyogenes in the biogenesis of virulence factors SpeB and the hemolysin streptolysin S (2004), Infect. Immun., 72, 1618-1625.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli strain DH5 alpha Streptococcus pyogenes

Protein Variants

Protein Variants Comment Organism
additional information mutant HTR10 with in-frame deletion in htrA, mutant HTR10 is unable to efficiently process the protease proprotein, shows a dramatic increase in hemolytic activity and is virulent in a murine model of subcutaneous infection, mutant HSC11 with a deletion control strain that is a sibling of mutant HTR10 but contains wild-type htrA Streptococcus pyogenes

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
group A streptococcus, strain HSC5
-

Purification (Commentary)

Purification (Comment) Organism
-
Streptococcus pyogenes

Synonyms

Synonyms Comment Organism
DegP
-
Streptococcus pyogenes
serine protease HtrA
-
Streptococcus pyogenes

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
30 40
-
Streptococcus pyogenes