Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N2-acetyl-N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]-L-leucinamide | inhibitor based on tetrapeptide hepsin inhibitor acetyl-KQLR-ketothiazole. Hepsin affinity of the (R)-epimer is similar to that of the corresponding (S)-epimer | Homo sapiens | |
N2-acetyl-N-[5-carbamimidamido-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]-L-leucinamide | inhibitor based on tetrapeptide hepsin inhibitor acetyl-KQLR-ketothiazole. Hepsin affinity of the (R)-epimer is similar to that of the corresponding (S)-epimer | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P05981 | - |
- |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000003 | - |
N2-acetyl-N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]-L-leucinamide | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
0.000022 | - |
N2-acetyl-N-[5-carbamimidamido-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]-L-leucinamide | pH not specified in the publication, temperature not specified in the publication | Homo sapiens |