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Literature summary for 3.4.21.106 extracted from
- Hepsin promotes prostate cancer progression and metastasis (2004), Cancer Cell, 6, 185-195.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | overexpression of hepsin in a mouse model of nonmetastasizing prostate cancer has no impact on cell proliferation, but causes disorganization of the basement membrane and promotes primary prostate cancer progression and metastasis to liver, lung and bones | Mus musculus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloned into the SpeI and EcoRI sites of the PB-IRES-hrGFP vector | Mus musculus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 31000 | - |
Western blot analysis, heavy chain of proteolytically processed hepsin | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| prostate epithelium | transgenic animals | Mus musculus | - |
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Release 2023.1 (January 2023)
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