Any feedback?
Literature summary for 3.4.21.105 extracted from
- Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases (2007), Genome Res., 17, 1634-1646.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Drosophila melanogaster |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Mus musculus |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Homo sapiens |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Saccharomyces cerevisiae |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Plasmodium falciparum |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Toxoplasma gondii |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Escherichia coli |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Providencia stuartii |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Pseudomonas aeruginosa |
| DNA and amino acid sequence analysis, phylogenetic analysis, overview | Bacillus subtilis |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Drosophila melanogaster | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Mus musculus | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Homo sapiens | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Saccharomyces cerevisiae | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Plasmodium falciparum | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Toxoplasma gondii | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Escherichia coli | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Providencia stuartii | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Pseudomonas aeruginosa | 16020 | - |
| membrane | the enzyme is an intramembrane serine protease, intramembrane rhomboid topology, modeling, overview | Bacillus subtilis | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Drosophila melanogaster | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | ? | - |
? |  |
| additional information | Mus musculus | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | ? | - |
? | |
| additional information | Homo sapiens | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | ? | - |
? | |
| additional information | Saccharomyces cerevisiae | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | ? | - |
? | |
| additional information | Plasmodium falciparum | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | ? | - |
? | |
| additional information | Toxoplasma gondii | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | ? | - |
? | |
| additional information | Escherichia coli | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | ? | - |
? | |
| additional information | Providencia stuartii | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | ? | - |
? | |
| additional information | Pseudomonas aeruginosa | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | ? | - |
? | |
| additional information | Bacillus subtilis | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | P54493 | gene yqgP or gluP | - |
| Drosophila melanogaster | - |
- |
- |
| Escherichia coli | P09391 | gene glpG | - |
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Plasmodium falciparum | - |
- |
- |
| Providencia stuartii | P46116 | gene aarA | - |
| Pseudomonas aeruginosa | Q9HZC2 | gene PA3086 | - |
| Saccharomyces cerevisiae | - |
- |
- |
| Toxoplasma gondii | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | Drosophila melanogaster | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | Mus musculus | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | Homo sapiens | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, and mitochondrial fusion | Saccharomyces cerevisiae | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | Plasmodium falciparum | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | Toxoplasma gondii | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | Escherichia coli | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | Providencia stuartii | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | Pseudomonas aeruginosa | ? | - |
? | |
| additional information | the enzyme is involved in regulation of growth factor signaling, mitochondrial fusion, and parasite invasion | Bacillus subtilis | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Drosophila melanogaster |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Mus musculus |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Homo sapiens |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Saccharomyces cerevisiae |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Plasmodium falciparum |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Toxoplasma gondii |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Escherichia coli |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Providencia stuartii |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Pseudomonas aeruginosa |
| More | determination and classification of intramembrane rhomboid topology, modeling, overview | Bacillus subtilis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AarA | - |
Providencia stuartii |
| GlpG | - |
Escherichia coli |
| PARL | - |
Mus musculus |
| Pcp1/Rbd1 | - |
Saccharomyces cerevisiae |
| RHBDL2 | - |
Homo sapiens |
| rhomboid intramembrane protease | - |
Drosophila melanogaster |
| rhomboid intramembrane protease | - |
Mus musculus |
| rhomboid intramembrane protease | - |
Homo sapiens |
| rhomboid intramembrane protease | - |
Saccharomyces cerevisiae |
| rhomboid intramembrane protease | - |
Plasmodium falciparum |
| rhomboid intramembrane protease | - |
Toxoplasma gondii |
| rhomboid intramembrane protease | - |
Escherichia coli |
| rhomboid intramembrane protease | - |
Providencia stuartii |
| rhomboid intramembrane protease | - |
Pseudomonas aeruginosa |
| rhomboid intramembrane protease | - |
Bacillus subtilis |
| rhomboid-1 | - |
Drosophila melanogaster |
| ROM1 | - |
Plasmodium falciparum |
| ROM4 | - |
Plasmodium falciparum |
| ROM5 | - |
Toxoplasma gondii |
| Yqgp | - |
Bacillus subtilis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
