Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.1 extracted from

  • Smoum, R.; Rubinstein, A.; Srebnik, M.
    A study of the effect on nucleophilic hydrolytic activity of pancreatic elastase, trypsin, chymotrypsin, and leucine aminopeptidase by boronic acids in the presence of arabinogalactan: a subsequent study on the hydrolytic activity of chymotrypsin by boronic acids in the presence of mono-, di-, and trisaccharides (2003), Bioorg. Chem., 31, 464-474.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(Cbz-alanyl)aminomethyl boronic acid inhibition decreases in the presence of arabinogalactan Bos taurus
(Cbz-phenylalanyl)aminomethyl boronic acid inhibition decreases in the presence of arabinogalctan Bos taurus
4-fluorophenylboronic acid
-
Bos taurus
phenylboronic acid
-
Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-Tyr-p-nitroanilide + H2O
-
Bos taurus benzoyl-tyrosine + p-nitroaniline
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.08
-
(Cbz-alanyl)aminomethyl boronic acid 37°C, pH 8.0 Bos taurus
1.96
-
(Cbz-phenylalanyl)aminomethyl boronic acid 37°C, pH 8.0 Bos taurus
9.7
-
phenylboronic acid 37°C, pH 8.0 Bos taurus
31.01
-
4-fluorophenylboronic acid 37°C, pH 8.0 Bos taurus