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Literature summary for 3.4.19.9 extracted from

  • Reisenauer, A.M.
    Folate conjugase: two separate activities in human jejunum (1977), Science, 198, 196-197.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
p-hydroxymercuribenzoate soluble intracellular enzyme is inhibited, membrane-bound brush-border enzyme not Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble intracellular Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
soluble intracellular enzyme, gel filtration Homo sapiens
91000
-
membrane-bound enzyme, gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pteroylpolyglutamate + H2O Homo sapiens folate conjugase in the brush-border may accomplish the initial digestion of the dietary pteroylpolyglutamates ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
two separate folate conjugase activities in jejunal mucosa: one membrane-bound and concentrated in the brush-border and the other soluble and intracellular
-

Source Tissue

Source Tissue Comment Organism Textmining
jejunum mucosal brush-border Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information soluble enzyme has a requirement for sulfhydryl groups in the active site Homo sapiens ?
-
?
pteroylpolyglutamate + H2O folate conjugase in the brush-border may accomplish the initial digestion of the dietary pteroylpolyglutamates Homo sapiens ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.5
-
soluble intracellular enzyme Homo sapiens
7.5
-
brush-border enzyme Homo sapiens