Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuroendocrine cell | UCHL1 is neuroendocrine cell-specific. Neuroendocrine gene expression in the large and small airway epithelium, UCHL1 is overexpressed in over 50% of lung cancers, overview | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ubiquitin carboxyl-terminal hydrolase L1 | - |
Homo sapiens |
UCHL1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | UCHL1 is consistently up-regulated in smokers compared with nonsmokers | up |
General Information | Comment | Organism |
---|---|---|
malfunction | UCHL1 is overexpressed in over 50% of lung cancers, its overexpression in chronic smokers may represent an early event in the complex transformation from normal epithelium to overt malignancy | Homo sapiens |
metabolism | ubiquitin carboxyl-terminal hydrolase L1 is a member of the ubiquitin proteasome pathway | Homo sapiens |
physiological function | UCHL1 is involved in the degradation of unwanted, misfolded, or damaged proteins within the cell | Homo sapiens |