Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.19.1 extracted from

  • Scaloni, A.; Barra, D.; Jones, W.M.; Manning, J.M.
    Human acylpeptide hydrolase. Studies on its thiol groups and mechanism of action (1994), J. Biol. Chem., 269, 15076-15084.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
iodoacetamide
-
Homo sapiens
N-acetyl-Met
-
Homo sapiens
p-nitrophenyl-N-propyl carbamate potent active site-directed, pseudo-first-order kinetics Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
2-naphthyl butyrate
-
Homo sapiens
0.02
-
p-nitrophenylbutyrate
-
Homo sapiens
0.06
-
4-nitrophenyl hexanoate
-
Homo sapiens
0.07
-
p-nitrophenylvalerate
-
Homo sapiens
0.16
-
p-nitrophenylpropionate
-
Homo sapiens
0.63
-
4-nitrophenyl acetate
-
Homo sapiens
1
-
butyryl thiocholine
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-naphthyl butyrate + H2O
-
Homo sapiens 2-naphthol + butanoate
-
?
4-nitrophenyl acetate + H2O
-
Homo sapiens 4-nitrophenol + acetate
-
?
butyryl thiocholine + H2O
-
Homo sapiens ?
-
?
N-acetyl-Ala p-nitroanilide + H2O
-
Homo sapiens N-acetyl-Ala + p-nitroaniline
-
?
naphthyl butyrate + H2O
-
Homo sapiens naphthol + butyrate
-
?
p-nitrophenyl acetate + H2O
-
Homo sapiens 4-nitrophenol + acetate
-
?
p-nitrophenyl butyrate + H2O
-
Homo sapiens ?
-
?
p-nitrophenyl hexanoate + H2O
-
Homo sapiens p-nitrophenol + hexanoate
-
?
p-nitrophenyl propionate + H2O
-
Homo sapiens p-nitrophenol + propionate
-
?
p-nitrophenyl valerate + H2O
-
Homo sapiens p-nitrophenol + pentanoate
-
?