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Literature summary for 3.4.18.1 extracted from

  • Kos, J.; Sekirnik, A.; Premzl, A.; Zavasnik Bergant, V.; Langerholc, T.; Turk, B.; Werle, B.; Golouh, R.; Repnik, U.; Jeras, M.; Turk, V.
    Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues (2005), Exp. Cell Res., 306, 103-113.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens cathespin X is involved in phagocytosis and regulation of immune response, not involved in degradation of extracellular matrix, a proteolytic event leading to tumor cell invasion and metastasis ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
dendritic cell
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 Homo sapiens
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lung protein level of cathespin X does not differ significantly between matched pairs of lung tumor and adjacent lung tissue ontained from patients with lung cancer Homo sapiens
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lung cancer cell protein level of cathespin X does not differ significantly between matched pairs of lung tumor and adjacent lung tissue ontained from patients with lung cancer Homo sapiens
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monocyte
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 Homo sapiens
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monocyte in germinal centers of secondary follicles in lymph nodes Homo sapiens
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additional information the cell lines MCF-10A neoT and MDA-MB 231 are negative for cathepsin Homo sapiens
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U-937 cell
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cathespin X is involved in phagocytosis and regulation of immune response, not involved in degradation of extracellular matrix, a proteolytic event leading to tumor cell invasion and metastasis Homo sapiens ?
-
 ?