Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-2-(3-((S)-1-carboxy-5-(3-(4-iodophenyl)ureido)pentyl)ureido)pentanedioic acid | i.e. MIP-1095, the compound shows affinity to and uptake into prostate cancer cells, binding analysis, overview | Homo sapiens | |
(S)-2-(3-((S)-1-carboxy-5-(4-iodobenzylamino)pentyl)ureido)pentanedioic acid | i.e. MIP-1072, the compound shows affinity to and uptake into prostate cancer cells, binding analysis, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
LNCaP cell | - |
Homo sapiens | - |
additional information | PC-3 cells lack PSMA | Homo sapiens | - |
prostate cancer cell | highly up-regulated PSMA | Homo sapiens | - |
prostate epithelium | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
glutamate carboxypeptidase | - |
Homo sapiens |
Prostate-specific membrane antigen | - |
Homo sapiens |
PSMA | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00000024 | - |
(S)-2-(3-((S)-1-carboxy-5-(3-(4-iodophenyl)ureido)pentyl)ureido)pentanedioic acid | - |
Homo sapiens | |
0.0000046 | - |
(S)-2-(3-((S)-1-carboxy-5-(4-iodobenzylamino)pentyl)ureido)pentanedioic acid | - |
Homo sapiens |