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Literature summary for 3.4.17.21 extracted from

  • Aggarwal, S.; Ricklis, R.M.; Williams, S.A.; Denmeade, S.R.
    Comparative study of PSMA expression in the prostate of mouse, dog, monkey, and human (2006), Prostate, 66, 903-910.
    View publication on PubMed
Search for more literature for 3.4.17.21

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-
membrane
-
 Homo sapiens 16020
-
membrane
-
 Canis lupus familiaris 16020
-
membrane
-
 Macaca mulatta 16020
-
membrane
-
 Macaca fascicularis 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc-metallopeptidase Mus musculus
Zn2+ zinc-metallopeptidase Homo sapiens
Zn2+ zinc-metallopeptidase Canis lupus familiaris
Zn2+ zinc-metallopeptidase Macaca mulatta
Zn2+ zinc-metallopeptidase Macaca fascicularis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O Mus musculus
-
 N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O Homo sapiens
-
 N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O Canis lupus familiaris
-
 N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O Macaca mulatta
-
 N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O Macaca fascicularis
-
 N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
 beagle dog
-
Homo sapiens
-
-
-
Macaca fascicularis
-
 cynomolgus monkey
-
Macaca mulatta
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast quantitative expression analysis Homo sapiens
-
DU-145 cell very low enzyme expression level Homo sapiens
-
LNCaP cell quantitative expression analysis Homo sapiens
-
PC-3 cell very low enzyme expression level Homo sapiens
-
prostate gland quantitative expression analysis Mus musculus
-
prostate gland quantitative expression analysis Homo sapiens
-
prostate gland quantitative expression analysis Canis lupus familiaris
-
prostate gland quantitative expression analysis Macaca mulatta
-
prostate gland quantitative expression analysis Macaca fascicularis
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity in prostate tissue homogenate in comparison to other species, overview Mus musculus
additional information
-
 activity in prostate tissue homogenate in comparison to other species, overview Homo sapiens
additional information
-
 activity in prostate tissue homogenate in comparison to other species, overview Canis lupus familiaris
additional information
-
 activity in prostate tissue homogenate in comparison to other species, overview Macaca mulatta
additional information
-
 activity in prostate tissue homogenate in comparison to other species, overview Macaca fascicularis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O
-
 Mus musculus N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O
-
 Homo sapiens N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O
-
 Canis lupus familiaris N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O
-
 Macaca mulatta N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O
-
 Macaca fascicularis N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O i.e. NAAG Mus musculus N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O i.e. NAAG Homo sapiens N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O i.e. NAAG Canis lupus familiaris N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O i.e. NAAG Macaca mulatta N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?
N-acetyl-alpha-L-aspartyl-L-glutamate + H2O i.e. NAAG Macaca fascicularis N-acetyl-alpha-L-aspartate + L-glutamate
-
 ?

Synonyms

Synonyms Comment Organism
Prostate-specific membrane antigen
-
 Mus musculus
Prostate-specific membrane antigen
-
 Homo sapiens
Prostate-specific membrane antigen
-
 Canis lupus familiaris
Prostate-specific membrane antigen
-
 Macaca mulatta
Prostate-specific membrane antigen
-
 Macaca fascicularis
PSMA
-
 Mus musculus
PSMA
-
 Homo sapiens
PSMA
-
 Canis lupus familiaris
PSMA
-
 Macaca mulatta
PSMA
-
 Macaca fascicularis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus
37
-
 assay at Homo sapiens
37
-
 assay at Canis lupus familiaris
37
-
 assay at Macaca mulatta
37
-
 assay at Macaca fascicularis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus
7.4
-
 assay at Homo sapiens
7.4
-
 assay at Canis lupus familiaris
7.4
-
 assay at Macaca mulatta
7.4
-
 assay at Macaca fascicularis