Literature summary for 3.4.17.21 extracted from

Thomas, A.G.; Vornov, J.J.; Olkowski, J.L.; Merion, A.T.; Slusher, B.S.
N-Acetylated alpha-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin (2000), J. Pharmacol. Exp. Ther., 295, 16-22.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
N-acetyl-Asp-Glu + H2O	Rattus norvegicus	the enzyme converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin	N-acetyl-Asp + Glu	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cell culture	cortical cells	Rattus norvegicus	-
cerebral cortex	cortical cells dissociated in cell culture	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-acetyl-Asp-Glu + H2O	-	Rattus norvegicus	N-acetyl-Asp + Glu	-	?
N-acetyl-Asp-Glu + H2O	the enzyme converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin	Rattus norvegicus	N-acetyl-Asp + Glu	-	?

Synonyms

Synonyms	Comment	Organism
N-acetylated alpha-linked acid dipeptidase	-	Rattus norvegicus
NAALADase	-	Rattus norvegicus

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Release 2023.1 (January 2023)