Literature summary for 3.4.17.20 extracted from

Ikeda, A.; Gabazza, E.C.; Morser, J.; Imoto, I.; Kuroda, M.; DAlessandro-Gabazza, C.N.; Hara, K.; Ruiz, D.B.; Bernabe, P.G.; Katsurahara, M.; Toda, M.; Kobayashi, Y.; Yano, Y.; Sumida, Y.; Suzuki, K.; Taguchi, O.; Takei, Y.
Presence of thrombin-activatable fibrinolysis inhibitor in Helicobacter pylori-associated gastroduodenal disease (2009), Helicobacter, 14, 147-155.

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Application

Application	Comment	Organism
medicine	TAFI is present in the gastric mucosa and it may play a role in the pathogenesis of Helicobacter pylori infection-associated gastroduodenal disorders	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	the gastric intramucosal concentrations of TAFI are measured by enzyme immunoassay. This study comprises 65 patients with gastroduodenal disorders. The gastric levels of TAFI and plasminogen activator inhibitor-1 are significantly increased in patients with Helicobacter pylori compared to those without infection or cured Helicobacter pylori	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
gastric mucosa	TAFI is detected in gastric mucosal epithelial cells. The concentration of TAFI is correlated with the degree of gastric mucosal atrophy, inflammation, and disease activity	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
TAFI	-	Homo sapiens
thrombin-activatable fibrinolysis inhibitor	-	Homo sapiens

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Release 2023.1 (January 2023)