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Literature summary for 3.4.17.20 extracted from

  • Guimaraes, A.H.; Bertina, R.M.; Rijken, D.C.
    A new functional assay of thrombin activatable fibrinolysis inhibitor (2005), J. Thromb. Haemost., 3, 1284-1292.
    View publication on PubMed
Search for more literature for 3.4.17.20

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required for enzyme activation Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrin + H2O Homo sapiens anti-fibrinolytic activity fibrin + Lys
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 genotypes 1040CC and 1040TT
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
-
blood plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 assay development and optimization, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrin + H2O anti-fibrinolytic activity Homo sapiens fibrin + Lys
-
 ?

Synonyms

Synonyms Comment Organism
TAFI
-
 Homo sapiens
thrombin activatable fibrinolysis inhibitor
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens